Evidence-led hair loss care

Treat the cause.
Support the follicle.
Stay with the plan.

Hair restoration is rarely one treatment or one appointment. We combine medical diagnosis, proven prescription options and carefully selected in-clinic adjuncts—then measure what is actually changing.

Before treatment

The diagnosis changes the plan.

Pattern hair loss is common, but shedding can also reflect iron deficiency, thyroid disease, medication, illness, hormonal change, inflammation or scarring alopecia.

We begin with history, scalp examination, medication and health screening, and baseline photography. Blood tests or specialist referral may be recommended when the pattern is unclear.

Medical foundation

Six options.
One individual plan.

Medication is selected by diagnosis, sex, medical history, pregnancy plans, risk tolerance and how reliably a treatment can be continued.

Off-label means a medicine is prescribed for a purpose outside its approved product indication; it does not mean “untested” or automatically unsuitable.

01

Established first-line option

Topical minoxidil

Applied directly to the scalp, topical minoxidil can help prolong the growth phase and support density in male and female pattern hair loss.

When it may fit

Often a practical starting point when the diagnosis is pattern hair loss and daily scalp application is realistic.

Important considerations

Scalp irritation, dryness, unwanted facial hair and an early increase in shedding can occur. Benefit generally requires continued use.

Randomised-trial meta-analysis comparing topical and oral minoxidil
02

Prescription · off-label for hair loss

Low-dose oral minoxidil

A systemic alternative when topical treatment is poorly tolerated, inconvenient or has not delivered a satisfactory response.

When it may fit

May be considered after blood-pressure, cardiovascular, medication and pregnancy-related screening.

Important considerations

Excess body or facial hair is common. Fluid retention, headache, dizziness, palpitations and blood-pressure changes are possible and require medical oversight.

Randomised clinical trial: oral 5 mg versus topical 5% minoxidil
03

Prescription · androgen pathway

Finasteride

Finasteride lowers dihydrotestosterone (DHT), addressing a key driver of follicle miniaturisation in male pattern hair loss.

When it may fit

Most often discussed for adult men with androgenetic alopecia. Suitability is individual and requires a medication and reproductive-health review.

Important considerations

Potential effects include reduced libido, erectile or ejaculatory symptoms, breast changes and mood symptoms. It must not be used during pregnancy; special handling precautions apply to broken tablets.

Systematic review: finasteride combined with topical minoxidil
04

Prescription · off-label for female pattern hair loss

Spironolactone

An anti-androgen option sometimes used for women, particularly when the pattern and clinical context suggest androgen sensitivity.

When it may fit

Considered after reviewing blood pressure, kidney function, potassium, other medicines and pregnancy plans.

Important considerations

May cause menstrual irregularity, breast tenderness, dizziness, increased urination and electrolyte changes. Reliable pregnancy avoidance is important while taking it.

Systematic review and meta-analysis in female pattern hair loss
05

Prescription · off-label for hair loss

Dutasteride

A more potent 5-alpha-reductase inhibitor that may be considered in selected patients when response to other medical treatment is insufficient.

When it may fit

Usually reserved for a carefully counselled plan because it has a long half-life and broader DHT suppression than finasteride.

Important considerations

Sexual, reproductive, breast and mood-related effects must be discussed. It is not used in pregnancy, and blood-donation restrictions may apply.

Systematic review and meta-analysis: dutasteride versus finasteride
06

Personalised · often multimodal

Combination therapy

Pattern hair loss has more than one therapeutic target. A well-chosen combination may address follicle cycling, androgen signalling and the scalp environment together.

When it may fit

Useful when a single therapy is unlikely to meet the treatment goal, or when progress has plateaued despite consistent use.

Important considerations

More is not automatically better. Every additional treatment adds cost, burden and potential side effects; the plan should remain measurable and reviewable.

Systematic review and meta-analysis of combination approaches

The early phase

Initial shedding can happen.
It is usually temporary.

Some people notice increased shedding in the first several weeks after starting minoxidil or changing treatment. This can occur as follicles move through the hair cycle—but not everyone experiences it.

Do not use shedding as proof that treatment is working. Contact the clinic if shedding is severe, prolonged, patchy, painful or accompanied by scalp inflammation or other symptoms.

In-clinic adjuncts

Add procedures with purpose—not by default.

These treatments are commonly used in our clinic alongside medical therapy when the diagnosis, evidence, downtime, budget and treatment goal align.

Laser adjunct

Fotona HAIRestart®

A non-invasive Er:YAG laser protocol designed to deliver controlled thermal stimulation to the scalp. In our clinic it may be paired with a medical foundation rather than positioned as a replacement for it.

Evidence position: Direct protocol evidence is still developing; related laser/light studies support a possible adjunct role, with outcomes varying by device and protocol.

View related evidence on PubMed

1927 nm thulium adjunct

LaseMD™ hair treatment

A fractional thulium-laser approach used to create controlled microchannels in the scalp and support a structured hair-restoration protocol.

Evidence position: Small clinical studies are encouraging, but the evidence base is less mature than for established medical therapies.

View related evidence on PubMed

Autologous biologic adjunct

PRP hair treatment

Platelet-rich plasma is prepared from your own blood and injected into the scalp. It may support hair density in appropriately selected patients.

Evidence position: Meta-analyses suggest a density benefit, while also finding major variation in protocols, study quality and reported outcomes.

View related evidence on PubMed

Emerging adjunct

Exosome hair treatment

Exosome-based products contain cell-signalling particles and are being studied for regenerative hair applications. Product source and manufacturing quality matter.

Evidence position: Clinical evidence remains early, heterogeneous and based on small studies. Long-term safety, ideal dosing and standardised protocols are not yet established.

View related evidence on PubMed

Why combine?

Medication remains the foundation. Procedures may add another signal.

For pattern hair loss, medical therapy targets the biological drivers that remain active between clinic visits. A procedure can complement that foundation, but it cannot replace consistency.

PubMed: evidence for combination therapy

A measured plan

Change is slow.
Tracking should not be.

Standardised photographs and planned reviews help distinguish real progress from normal day-to-day variation.

Read the safety essentials
  1. 01

    Diagnose + document

    Confirm the likely cause, identify aggravating factors and record a reproducible baseline.

    Day 0
  2. 02

    Build the foundation

    Choose the smallest sensible medical plan, explain side effects and agree on what consistency looks like.

    Weeks 0–4
  3. 03

    Add an adjunct—if useful

    Consider Fotona, LaseMD, PRP or exosome treatment only where it adds a clear role to the plan.

    Plan dependent
  4. 04

    Review + refine

    Assess tolerability first, then compare density, calibre, shedding and photography over a meaningful interval.

    3–12 months

Safety essentials

The right treatment is the one that is safe for you.

Prescription review

All oral options require a clinician review of medical history, other medicines, blood pressure and relevant monitoring.

Pregnancy + fertility

Finasteride, dutasteride and spironolactone have important reproductive restrictions. Minoxidil also requires pregnancy and breastfeeding discussion.

Report side effects

Do not quietly persist through concerning symptoms. Early review allows the dose, formulation or entire strategy to be reconsidered.

Seek prompt medical review

Not all hair loss should wait.

  • Sudden, rapid or patchy hair loss
  • Scalp pain, marked itch, redness, scale, pustules or scarring
  • Loss of eyebrows, eyelashes or body hair
  • Hair loss with fatigue, weight change, menstrual change or systemic illness

Your next step

Start with a diagnosis.
Leave with a plan.

A medical hair-loss consultation is designed to clarify what is happening, what is worth treating and what is unlikely to help.

Contact our clinic team to arrange an assessment. Bring a current medication list, relevant blood-test results and any previous treatment history.

Prepare for your assessment