Hands off
Do not rub, squeeze, pick or repeatedly check the tiny bumps. Touch only with freshly washed hands when gentle cleansing or skincare is needed.
MA360 patient aftercare · Sydney
The entry points are tiny and begin sealing quickly, so recovery is usually straightforward. For the first day, the essentials are clean hands, gentle skincare and less touching—not a complicated routine.
Your one-page summary
Rejuran and injectable skin boosters use fine needles or a cannula. The punctures are small, but the treated skin can still be swollen, sensitive and easier to irritate for a short time.
Do not rub, squeeze, pick or repeatedly check the tiny bumps. Touch only with freshly washed hands when gentle cleansing or skincare is needed.
Leave the skin alone for the first four hours. That evening, if there is no active oozing, use lukewarm water and a mild cleanser, then pat dry.
Wait until the next morning for makeup. Avoid hard exercise, alcohol and intense heat for 24 hours, and pause retinoids or exfoliating acids for 48–72 hours.
The first 24 hours
The exact appearance depends on the product, treatment area, injection technique and your tendency to swell or bruise. Your personalised instructions take priority.
Do not wash, apply makeup or massage. If a point oozes, lightly dab it once with clean gauze. A wrapped cool pack can be used briefly without pressure.
With clean hands, use a gentle fragrance-free cleanser and lukewarm water. No scrub, cleansing brush or face cloth. Pat dry with a clean towel.
Use a clean pillowcase and avoid deliberate pressure on the treated area. Do not squeeze the small raised blebs; they normally soften and flatten on their own.
If the skin is dry and calm, apply a plain moisturiser, SPF 50+ and clean makeup gently. Wait longer if points are still weeping, crusted or very irritated.
Recovery
Mild injection-site reactions should remain stable or gradually improve. Bumps can be more obvious immediately after superficial treatment, particularly around the eyes.
Frequently asked questions
These are conservative general instructions for injectable Rejuran and skin boosters. A “skin booster” is a broad category, so advice may differ by product, treatment area or combination procedure.
The simplest rule is to wait until the next morning—about 12 to 24 hours. This avoids applying pigment, brushes or sponges over fresh injection points during the most sensitive period.
If any point is still oozing, crusted, very red or tender, wait longer. When you restart, wash your hands and use clean brushes or sponges. Apply lightly without pressing the bumps.
Leave the area alone for the first four hours. Later that day, if there is no active bleeding or oozing, wash with clean hands, lukewarm water and a mild fragrance-free cleanser.
Use light pressure. Do not scrub, exfoliate, use a cleansing device or drag a face cloth over the skin. Pat dry with a clean towel.
You do not need to keep your face completely dry, and you should not keep it deliberately wet or occluded. The tiny punctures begin sealing quickly, but there is no exact closure time that applies to every needle, treatment area and person.
A brief gentle cleanse is appropriate once there is no oozing. Pat dry afterwards. Avoid soaking, steam rooms, swimming and prolonged hot showers during the first 24 hours.
If the skin feels tight, a plain fragrance-free moisturiser can be used once the injection points are dry. Avoid heavily fragranced products and do not cover weeping points with thick occlusive creams unless your clinician advised it.
Use shade and a hat on treatment day. Broad-spectrum SPF 50+ can usually be applied the next morning, or once the entry points are closed and dry.
Pause retinoids, exfoliating acids, scrubs, benzoyl peroxide and other potentially irritating actives for about 48–72 hours and until redness or sensitivity has settled.
Not every vitamin C formula is irritating, but if it stings, leave it out. Restart products one at a time rather than returning to a full active routine immediately.
A brief lukewarm shower is usually fine. For 24 hours, avoid strenuous exercise, alcohol, saunas, steam rooms, hot baths and other intense heat. These restrictions are precautionary and may help limit flushing, swelling and irritation.
Normal light activity is fine. If the treatment area is still very swollen or bruised the next day, ease back into exercise.
No—unless your treating clinician specifically asks you to. Small raised blebs are expected with superficial Rejuran or skin booster injections and usually flatten as the product disperses and swelling settles.
Do not squeeze, press or try to “smooth out” individual points. Aftercare for Rejuran is not the same as the massage routine used for some other injectable products.
Small bumps often flatten over the first day or two. Puffiness may be more noticeable the following morning, particularly around the eyes. Bruising can become clearer before it fades and may take several days.
A systematic review of polynucleotide studies described local pain, swelling, redness, itching, bruising and irritation as generally mild and transient, typically resolving within a week. Individual recovery varies.
Avoid facial massage, microneedling, waxing, peels, lasers and energy-based procedures until the skin has settled and your clinician has confirmed appropriate timing. One to two weeks is a common minimum interval, but combination plans and treatment areas differ.
Tell every practitioner what was injected, where and when before another procedure.
No special diet or extreme water intake is required. Eat normally and stay comfortably hydrated. Avoid starting supplements or medicines purely to prevent bruising without medical advice.
Do not stop prescribed aspirin, anticoagulants or other medicines unless the prescribing clinician tells you to.
Safety first
If a symptom is becoming stronger rather than settling, please contact us early. A photograph and short conversation can often clarify the next step.
Evidence behind the guide
Direct clinical trials comparing exact Rejuran aftercare routines are limited. Published evidence is strongest for expected short-term reactions and general injectable skincare principles; several timing rules remain conservative clinical precautions.
Supports a simple baseline routine built around cleanser, moisturiser and broad-spectrum SPF 50+, while noting the limited direct guidance available.
Found promising but low-to-moderate-quality evidence. Reported effects included temporary pain, swelling, redness, itch, bruising and irritation.
Provides practical post-injection principles, complication warning signs and transparent acknowledgement that several routine restrictions are precautionary.
Shows that small needle-created channels begin recovering promptly. Microneedling is not identical to injectable Rejuran, so it cannot define one universal puncture-closure time.
This page provides general aftercare information and does not replace an examination, diagnosis or the instructions given for your specific product, technique and treatment area.
Continue with MA360
Learn more about the treatment you received, compare related skin-quality options or open the aftercare guide that matches another procedure.
Understand Rejuran Classic, Rejuran i, Rejuran s and doctor-led treatment planning.
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↗Written and medically reviewed
Medical Aesthetics 360 · Last reviewed 19 August 2026
Personalised support
If your treating clinician gave different instructions, follow those. If you are uncertain about swelling, bruising, skincare or your next treatment, contact the MA360 team rather than trying to diagnose it yourself.
General information only. Suitability, recovery and results vary. This guide does not replace personalised medical advice or emergency assessment.
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